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Genome SEGE - Intronless Genes in Eukaryotes
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| Overview
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Intronless Genes in Eukaryotes Intron-containing genes are characteristic features of many intron rich multicellular eukaryotic genomes. Surprisingly multicellular genomes contain a considerable amount of intronless genes. Many eukaryotic intronless genes without further evidence of retro-transposition are known. Some intronless genes with evidence of retro-transposition origin and lost function are also known. Despite the availability of such information, our knowledge on these genes on a genomic scale is substantially limited. Genome-wide functional assignments using bioinformatics tools are performed and the results are available for download and search. We completed this assignment procedure using the following steps. 1. Single exon genes are identified using the CDS FEATURE definition in the genome data. 2. Potential pseudogenes are identified by scanning for a polyA tail within 1000 nt from the stop codon and are preceded by a polyA signal. 3. Sequences corresponding to pseudogenes are removed from further analysis. 4. PROSITE motifs are then located in each intronless
gene product from each genome. Please mail comments and queries to mmeena@ntu.edu.sg |
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