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SEGE - Single Exonic Genes in Eukaryotes
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Overview
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Description Most eukaryotic genes are multi-exonic with their gene structure being interrupted by non-coding introns. Introns in eukaryotic genes account for a major proportion of many eukaryotic genomes. For example approximately 24% of the human genome is shown to be introns compared to 1.1 % exons. Several databases have been built to describe the exon-intron structures in eukaryotic genes. The discovery of introns obscured the fact that many eukaryotic genes actually have a prokaryotic architecture that is they do not have introns. Although most genes in eukaryotes contain introns, there are many reports on intronless genes. However, there is no comprehensive database for intronless genes to study them in a concerted manner. Such a database will be useful to identify commonalities in genes having single exonic structure within and across genus/species. The proportion of intron-less genes in eukaryotes is not exactly estimated in almost all the model organisms whose complete genome sequences are available. The availability of annotated sequence data in the GenBank makes it possible to study these genes in greater details. In the present report we describe a database of intronless genes in eukaryotes using GenBank data version 138. This database, which we call SEGE (Single Exonic Genes in Eukaryotes), is a collection of gene sequences that are annotated to have single exon structure in Genbank feature table. The data is clustered into several divisions to facilitate easy retrieval and analysis. Please mail comments and queries to mmeena@ntu.edu.sg |
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